Nothing is impossible for the determined - with effort, anything can be done.
Tips
history
This folk saying appears as early as the Song dynasty and became fixed in the form 世上无难事,只怕有心人. 毛泽东 reworked it in his poem 《水调歌头·重上井冈山》 as 世上无难事,只要肯登攀 ('nothing in the world is hard, so long as you are willing to climb').
usage
Almost always paired with the following line 只怕有心人, encouraging people that anyone who sets their mind to a task can succeed.