Yǐ tā de shílì duìfù zhège duìshǒu, jiǎnzhí shì wěnyíng.
With his skill level against this opponent, it's a guaranteed win.
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稳赢 is informal and colloquial, often used in gaming, sports, or casual competition contexts. More formal alternatives: 必胜 (certain to win) or 胜券在握 (holding the winning ticket).