However many setbacks he meets, he never loses heart.
Tips
usage
Modern use is overwhelmingly 气馁 ('to lose heart / be discouraged'), most often negated: 不气馁 (to not give up). The original 'hungry' sense is now archaic.
Food radical on the left, side-form of 食. It points to the original sense 'hungry, starving'; from an empty stomach came the figurative 'low-spirited, deflated.' Same family as 饿 hungry and 饱 full.