Tā duìdài dírén cóngbù shǒuruǎn, zǒngshì gǎnjìn-shājué.
He never shows weakness toward enemies and always wipes them out completely.
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usage
赶尽杀绝 is used to describe ruthless, total elimination with no survivors or escape. It can describe actual violence or, more commonly, a figurative determination to destroy competition or opposition entirely.