Tā duì gānjìng de zhízhuó jiǎnzhí xiàng ge piānzhíkuáng.
His obsession with cleanliness borders on monomania.
Tips
usage
In clinical use, refers to delusional disorder (fixed paranoid beliefs). In everyday speech, often used loosely for any obsessive perfectionist - Andy Grove's 'Only the Paranoid Survive' is translated as 《只有偏执狂才能生存》.