Recorded in the Han-dynasty
神农本草经 (Shénnóng Běncǎo Jīng, 'Shennong's Herbal Classic'). The dried, bitter, yellow-brown melon-stem part is used in small doses to induce vomiting; classical recipes pair it with
赤小豆 (chìxiǎodòu, 'adzuki bean') in the formula
瓜蒂散 (guādì sǎn).