In traditional Chinese medicine
乌头 (Aconitum carmichaelii root) is a famous
大毒 (dà dú, highly toxic) herb that must be carefully processed (
炮制 páozhì) before use — its derivatives
附子 (fùzǐ) and
川乌 (chuānwū) are core 'warming yang' drugs. Improperly prepared, it has caused many fatal poisonings.