Wǒmen duì yǔzhòu de qǐyuán réngrán zhīzhī-shènshǎo.
We still know very little about the origin of the universe.
Tips
grammar
知之甚少 follows the classical pattern: 知 (know) + 之 (it / object marker) + 甚 (very / extremely) + 少 (little / few). The 之 refers back to the topic being discussed, often introduced by 对.