Long-term drinking caused a red rosacea-like rash on his nose.
Tips
register
Archaic — definitions follow classical attestation only. The standard modern term for rosacea is 酒糟鼻 ('drinker's nose') or, in medical writing, 玫瑰痤疮. You encounter 皻 only in classical / TCM medical texts, where it appears as a variant of 齇.
Left 皮 (Kangxi #107, skin) — anchors the meaning unambiguously in a skin condition. Pairs with 皴 (chapped) and 皲 (cracked) in the skin-condition family.