Internet-era slang that peaked around 2013-2015 on Weibo. Half-confused, half-exasperated — you aim it at someone whose behavior makes no sense. 闹 literally 'to make a fuss', 哪样 'what kind'.
usage
Often drawn out as 你闹哪样啊? with a whining 啊. Not rude per se, but not something to say to your boss — reserve for friends, family, or online venting.