R yāo sān sì a shì yǐqián chángyòng de qìchē lěngméi.
R134a used to be the standard refrigerant in cars.
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冷 'cold' + 媒 'medium / agent' — literally 'cold medium,' the fluid that carries cold. Mainland mechanics also say 制冷剂 (zhìlěngjì); 冷媒 is more common in Taiwan and in written technical texts.