He's a lovable airhead — all his friends adore him.
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Internet slang, mostly affectionate. Calling a friend 二货 is teasing, not insulting; calling a stranger this is rude. The 二 here taps northern slang where 二 means 'foolish' or 'half-baked' (cf. 二百五).
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Think 'category two goods' — defective merchandise that didn't pass first-grade inspection. The slang sense extends the same logic to people who 'don't quite work right.'