She cannot handle the exhaustion of long-distance travel.
Tips
grammar
经不起 is a potential complement structure: 经 (to undergo/withstand) + 不 (cannot) + 起 (up to). Its affirmative form 经得起 means 'can withstand.' Common collocations: 经不起考验 (cannot withstand a test), 经不起诱惑 (cannot resist temptation).