As a teacher, I deeply feel the weight of the long road ahead.
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From 《论语·泰伯》 where Zeng Zi says: 士不可以不弘毅,任重而道远 - a scholar must be resolute because the burden (benevolence itself) is heavy and the journey long. Strong Confucian overtones.
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Formal and slightly self-sacrificial in tone. Used when accepting a serious long-term responsibility - speeches, editorials, inauguration statements.