More literary than spoken 生气 (shēngqì). Common collocations: 勃然大怒 (suddenly furious), 龙颜大怒 (the dragon countenance — i.e. emperor — flies into a rage).
memory
大 (great) + 怒 (anger). The character 怒 places 心 (heart) under 奴 — anger as the heart enslaved.