chuāng is the older, original sense — a cut or wound from a blade — and stays restricted to medical and figurative-damage contexts. Common compounds:
创伤 (wound; trauma — also psychological),
创口 (the wound opening),
创可贴 (adhesive bandage, Band-Aid),
重创 (to inflict heavy damage on),
心理创伤 (psychological trauma),
创伤后应激障碍 (PTSD). The four-character
创巨痛深 describes deep, lasting distress.